A small village in the province of Teramo, located in the area once inhabited by the Sabines and under the influence of the Roman colony of Hatria, Penna Sant'Andrea owes its name, attested since 1273, to its nearby locality of Pinna, where a church dedicated to the patron Saint was edified. In 991 it became part of the jurisdiction of Monte Cassino, and later in the Norman period, it was submitted to Oderisio of Collepetroso. Over the centuries it was ruled by local noble families, that kept it, in juridical terms, tied to the nearby Atri.

Not to miss:
- the Parish Church of Santa Maria del Soccorso, dating back to the XVI century and restored in the XVIII century, it features important and valuable furnishings from the desecrated Church of St. Giusta and a XVII century altarpiece;
- the Church of Santa Maria di Podio, of medieval origins;
- the Church of the Holy Trinity (XIV century);
- Fontevecchia (1400);
- the Nature Reserve of Castel Cerreto.