Domina Home Kyrie is located on the island of San Domino, the lushest and most charming of the five islands that make up the Tremiti Archipelago, characterised by rocky cliffs, quaint beaches and marine caves, making it a true paradise for scuba diving aficionados. A protective thicket surrounds the hotel l located just a few steps from the sea, creating suggestive plays of shadows and light.

Various paths allow visitors to explore the island's inland area which hold incredible archaeological treasures dating back to the Roman ages and churches such as Santa Maria a Mare with its majestic portal.

Domina Home Kyrie has 62 rooms all with private bathroom, direct line telephone, television, mini-bar and air conditioning. An additional 24 Suites were built to meet the high demand for this extremely special place. The main hall is a large living room where guests can talk or peacefully relax, located near the swimming pools. The entire structure was recently remodernized and additional improvement work is scheduled for 2007.

The Domina Kyrie also has a restaurant, bar, piano bar, room service, parking lot and helicopter service.