These are the most important spas in Marche with the classification of their thermal waters:

- Acquasanta Terme (AP): sulphureous and salso-bromo-iodic water (38.6°C);
- Camerano (AN): salso-bromo-iodic water;
- Fano (PU): salso-bromo-iodic, sulphureous, bicarbonate-alkaline-magnesiac and chlorinated water;
- Fermo (AP): bicarbonate-calcic water;
- Genga (AN): sulphureous-sodic water;
- Macerata Feltria (PU): sulphureous water;
- Petriano (PU): sulphureous water;
- Sarnano (MC): salso, sulphureous, bicarbonate-calci-sodic water;
- Tolentino (MC): bicarbonate-calcic water.